Platelet Function Disorders - Healthcare Utilization in Hospitalized Children

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منابع مشابه

Platelet function disorders.

Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery. As the complex internal biochemical and signal transduction pathways are further...

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Disorders of platelet function.

Careful study of the hereditary defects of platelet function, like that of the congenital coagulation disorders, has made a large contribution to our understanding of the normal haemostatic mechanism. I should like today to discuss the evolution of knowledge about this uncommon group of disorders to indicate how they help to advance our understanding of normal platelet physiology, and to point ...

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Acquired disorders of platelet function.

Platelet dysfunction is commonly acquired due to medications, procedures, medical conditions, and underlying hematologic disease. These issues are presented, the data reviewed, and recommendations given herein. Many medications and dietary supplements have platelet-inhibitory effects in vitro, although the clinical effects on bleeding risks are unclear for many. Platelet-inhibitory drugs are ke...

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Acquired disorders of platelet function.

A qualitative abnormality of platelet function should be considered in patients with mucocutaneous bleeding in the absence of thrombocytopenia or von Willebrand disease. Antiplatelet drugs are the most common cause of acquired platelet disorders leading to bleeding. Uremia, hepatic cirrhosis, myeloma and related disorders, polycythemia vera, essential thrombocythemia, and cardiopulmonary bypass...

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Platelet disorders in children: A diagnostic approach.

The investigation of children with suspected inherited platelet disorders is challenging. The causes of mucocutaneous bleeding are many, and specialized testing for platelet disorders can be difficult to access or interpret. An algorithm developed for the investigation of suspected platelet disorders provides a sequential approach to evaluating both platelet function abnormalities and thrombocy...

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ژورنال

عنوان ژورنال: Open Access Journal of Biogeneric Science and Research

سال: 2020

ISSN: 2692-1081

DOI: 10.46718/jbgsr.2020.02.000045